The best audio interface with MIDI ports combines dependable recording, low-latency monitoring, and convenient hardware control in one setup. The right model can connect microphones, instruments, MIDI keyboards, and outboard gear without unnecessary complexity.
Our selection covers practical two-input interfaces, expandable four-input options, and higher-end models with onboard processing, helping you match features and budget to your workflow.
Best 10 Audio Interface with Midi Ports Picks for 2026
Flexible 4x4 Workhorse
- 4x4 USB audio with MIDI I/O
- Four MIDAS mic preamps with phantom power
- 24-bit/192 kHz support and metal chassis
Best For: Home studios needing multiple inputs and MIDI connectivity
Modern Studio Hub
Focusrite Scarlett 4i4 4th Gen
- MIDI I/O with four line inputs and outputs
- Two mic preamps and two Hi-Z inputs
- Auto Gain, Clip Safe, Air mode, and 192 kHz support
Best For: Musicians building a flexible desktop recording setup
Simple MIDI Bridge
- One five-pin MIDI input and output
- Plug-and-play USB-C connection
- Supports mobile and desktop operating systems
Best For: Connecting five-pin MIDI gear to USB-C devices
Portable Vintage-Tone Pick
- Two-channel USB-C interface with MIDI
- 610-style Vintage mode
- 24-bit/192 kHz support for mobile recording
Best For: Mobile musicians and creators needing two channels and MIDI
Best Budget MIDI Pick
- MIDI I/O with 2-in/2-out recording
- Two Onyx preamps with 48V phantom power
- Bus-powered with zero-latency monitoring
Best For: Home musicians needing affordable MIDI and two-channel recording
Best for First-Time Creators
Focusrite Scarlett 2i2 4th Gen
- Two preamps and two Hi-Z inputs
- Auto Gain, Clip Safe, and Air modes
- Includes a broad recording software bundle
Best For: Beginners recording vocals, guitars, and other two-channel sources
Best Advanced MIDI-Adjacent Hub
- Four preamps and 14-in/10-out expansion
- 37 included real-time Synergy Core effects
- Dual USB-C with loopback and mobile routing
Best For: Producers and streamers needing flexible multi-device routing
Best Value MIDI Recording Hub
- MIDI I/O with two mic and instrument channels
- 24-bit/96 kHz recording and playback
- USB bus-powered with useful software included
Best For: Home recordists and keyboard players on a budget
Best Budget Streaming Pick
- Dual combo inputs for mic, line, and instrument sources
- Zero-latency USB/Direct monitoring
- Compact option for recording, podcasting, and streaming
Best For: Beginners and content creators needing flexible two-input recording
Best High-Resolution Solo Interface
Focusrite Scarlett Solo 4th Gen
- 24-bit/192 kHz recording with 120 dB dynamic range
- One mic preamp plus one Hi-Z instrument input
- Air modes and a broad software bundle
Best For: Solo vocalists and guitarists seeking detailed recordings
Flexible 4×4 Workhorse – Behringer U-PHORIA UMC404HD
The Behringer U-PHORIA UMC404HD is a practical audio interface with MIDI ports for home studios that need several simultaneous connections. Its four inputs, four outputs, MIDI I/O, four MIDAS-designed preamps, and 24-bit/192 kHz support make it well suited to recording microphones, instruments, and external MIDI gear.
Best For: Home recordists who need four-input/four-output connectivity and MIDI integration at an accessible price.
Pros:
- Four mic preamps with +48V phantom power support.
- 4×4 USB audio routing plus one MIDI input and output.
- Supports up to 24-bit/192 kHz recording.
- Impact-resistant metal chassis is built for regular use.
Cons:
- Its larger footprint is less convenient for compact mobile setups.
- Listed operating-system compatibility is older than that of many newer interfaces.
Choose the UMC404HD if your priority is connection count and straightforward MIDI-enabled recording. It is a capable studio hub for users who can make use of four analog inputs rather than needing the smallest possible interface.
Modern Studio Hub – Focusrite Scarlett 4i4 4th Gen
The Focusrite Scarlett 4i4 4th Gen is a versatile audio interface with MIDI ports for musicians working with microphones, guitars, synths, drum machines, and line-level gear. It combines MIDI I/O with four line inputs, four line outputs, two mic preamps, two Hi-Z instrument inputs, and useful recording aids such as Auto Gain and Clip Safe.
Best For: Musicians who want a current, flexible desktop interface for instruments, line-level equipment, and MIDI hardware.
Pros:
- Includes MIDI input and output alongside extensive analog connectivity.
- Two mic preamps and two Hi-Z instrument inputs cover common recording needs.
- 120 dB dynamic range and up to 24-bit/192 kHz operation.
- Air mode, Auto Gain, and Clip Safe support easier recording.
Cons:
- Its feature set may be more than needed for simple two-input recording.
- USB-C power and connectivity requirements may add setup considerations for some systems.
The Scarlett 4i4 is a strong all-around choice when MIDI is only one part of a broader studio setup. Its combination of inputs, outputs, recording controls, bundled software, and broad Mac, Windows, and iOS support gives it room to grow with a project.
Simple MIDI Bridge – FORE T1 USB-C MIDI Interface
The FORE T1 is a compact MIDI-to-USB-C solution for connecting traditional five-pin MIDI equipment to a computer, phone, or tablet. Although it is not an audio interface, it can complement an audio interface with MIDI ports by adding a dedicated MIDI connection for keyboards, synthesizers, electronic drums, and other compatible devices.
Best For: Users who need a dedicated, plug-and-play connection between five-pin MIDI hardware and USB-C devices.
Pros:
- Provides one MIDI input and one MIDI output across 16 channels.
- Plug-and-play operation with built-in driver support.
- USB bus-powered design with LED indicators for power and signal activity.
- Works with iOS, Android, Mac, and Windows systems.
Cons:
- Does not record or process audio; it is a MIDI interface only.
- A USB A-C adapter is not included.
- Requires compatible five-pin DIN MIDI ports on the external device.
This is best viewed as an accessory rather than a replacement for an audio interface with MIDI ports. It makes sense for a keyboardist or producer who already has audio hardware and needs a straightforward way to bring legacy MIDI gear into a USB-C workflow.
Portable Vintage-Tone Pick – Universal Audio Volt 2
The Universal Audio Volt 2 is a compact two-channel audio interface with MIDI for musicians, podcasters, and streamers who want portable recording with a vintage-inspired option. It offers 24-bit/192 kHz conversion, two-channel connectivity, 610-style Vintage mode, and support for Mac, Windows, iPad, and iPhone setups.
Best For: Mobile creators and musicians who need two recording channels, MIDI connectivity, and a vintage preamp option.
Pros:
- Two-channel USB-C interface with MIDI functionality.
- Vintage mode is designed to emulate UA’s classic 610 preamp character.
- Supports up to 24-bit/192 kHz recording.
- Compact design supports desktop and mobile recording workflows.
Cons:
- Two input channels provide less expansion than four-channel alternatives.
- Mobile iPhone use may require an Apple Lightning to USB Camera Adapter.
- External Volt power is required for operation.
The Volt 2 is a sensible pick when portability and tone are more important than a large I/O count. Its two-channel format keeps the setup simple, while MIDI and Vintage mode add useful flexibility for solo musicians, streamers, and compact production rigs.
Best Budget MIDI Pick – Mackie Onyx Producer 2-2
Mackie Audio Interface, Onyx Producer 2X2 USB Audio Interface with MIDI (Onyx Producer 2-2)
Check Price On AmazonIf you need an audio interface with MIDI ports for straightforward home recording, the Mackie Onyx Producer 2-2 combines MIDI I/O with two mic preamps, instrument-ready inputs, and 24-bit/192kHz recording. Its bus-powered USB 2.0 design also suits mobile setups.
Best For: Musicians who want MIDI connectivity, two-channel recording, and simple portable operation.
Pros:
- MIDI I/O and 2-in/2-out recording support
- Two Onyx mic preamps with 48V phantom power
- Combo inputs accept mic, line, and Hi-Z sources
- Zero-latency direct monitoring and bus-powered USB operation
Cons:
- Limited to two simultaneous input channels
- USB 2.0 connectivity is less current than USB-C
The Onyx Producer 2-2 is a practical choice when MIDI ports and core recording features matter more than expanded I/O or newer connection standards.
Best for First-Time Creators – Focusrite Scarlett 2i2 4th Gen
The Focusrite Scarlett 2i2 4th Gen is a polished two-channel interface for recording vocals and instruments. While it is not listed with MIDI ports, its 24-bit/192kHz conversion, Auto Gain, Clip Safe, Air modes, and bundled software make it a strong general-purpose alternative for creators comparing an audio interface with MIDI ports.
Best For: Beginners and songwriters prioritizing easy recording, modern USB-C connectivity, and included production software.
Pros:
- Two mic preamps and two Hi-Z instrument inputs
- 120dB dynamic range with recording up to 24-bit/192kHz
- Auto Gain and Clip Safe help manage recording levels
- Includes Pro Tools Intro+, Ableton Live Lite, Cubase LE, and Hitmaker Expansion
Cons:
- Supplied notes do not list MIDI I/O
- Only two input channels are available
The Scarlett 2i2 is especially appealing if your setup centers on microphones and guitars rather than external MIDI hardware, with useful safeguards that simplify the recording process.
Best Advanced MIDI-Adjacent Hub – Antelope Audio Zen Quadro
For buyers seeking an audio interface with MIDI ports alongside more expansive routing, the Antelope Audio Zen Quadro offers a portable four-preamp studio hub with dual USB-C, S/PDIF, ADAT expansion, and real-time Synergy Core effects. The supplied specifications do not list dedicated MIDI I/O, so verify compatibility with your MIDI hardware before buying.
Best For: Mobile producers, streamers, and small studios needing flexible routing, multiple inputs, and onboard processing.
Pros:
- Four Discrete preamps with up to 75dB of gain
- 37 included real-time effects using DSP and FPGA processing
- Dual USB-C supports computer-plus-mobile workflows and loopback
- Expandable 14-in/10-out design with ADAT and S/PDIF
Cons:
- Dedicated MIDI ports are not listed in the supplied specifications
- More features may be unnecessary for basic two-channel recording
- Advanced routing and effects can require a steeper learning curve
The Zen Quadro is the most capable option here for expandable routing and multi-device workflows, but buyers specifically requiring hardware MIDI ports should confirm the connection details first.
Best Value MIDI Recording Hub – PreSonus AudioBox 96
The PreSonus AudioBox 96 is a practical audio interface with MIDI ports for personal recording setups, portable studios, and musicians who want two microphone or instrument channels without needing a separate power supply. Its USB bus power, MIDI I/O, and 24-bit/96 kHz support make it a flexible starting point for computer-based recording.
Best For: Home recordists, keyboard players, and budget-conscious musicians who need MIDI connectivity alongside two-channel audio recording.
Pros:
- Includes MIDI I/O, two Class-A mic preamps, and two high-headroom instrument inputs.
- Supports recording and playback up to 24-bit/96 kHz.
- USB bus-powered design is convenient for mobile recording.
- Includes Studio One Artist, Ableton Live Lite, and the Studio Magic Plug-In suite.
Cons:
- Global +48V phantom power may be less flexible when mixing microphone types.
- It has two channels rather than a larger multichannel configuration.
Choose the AudioBox 96 when MIDI hardware and straightforward two-channel recording matter more than advanced expansion. The mixer control and zero-latency monitoring also make it well suited to simple vocal, guitar, and keyboard workflows.
Best Budget Streaming Pick – M-AUDIO M-Track Duo
The M-AUDIO M-Track Duo is an affordable audio interface with MIDI ports for users who want a compact setup for recording, podcasting, or live streaming. Its dual combo inputs accept microphones, line-level sources, or instruments, while the USB/Direct switch supports zero-latency monitoring.
Best For: Beginners, podcasters, streamers, and musicians who need flexible two-input recording with MIDI hardware compatibility.
Pros:
- Two combo XLR/line/instrument inputs support a range of sources.
- Offers phantom power, headphone monitoring, and stereo main outputs.
- USB/Direct monitoring switch helps reduce monitoring latency.
- Includes MPC Beats software and supports Mac, PC, iOS, and Android systems.
Cons:
- Maximum sample rate is 48 kHz, below some competing interfaces.
- The supplied notes list MIDI hardware compatibility, but do not specify dedicated MIDI I/O ports.
The M-Track Duo is a sensible low-cost option when everyday recording and streaming features are the priority. Buyers specifically needing physical five-pin MIDI input and output should verify the port configuration before choosing it.
Best High-Resolution Solo Interface – Focusrite Scarlett Solo 4th Gen
The Focusrite Scarlett Solo 4th Gen is a compact audio interface with MIDI hardware compatibility for songwriters recording one microphone and one instrument at a time. Its 24-bit/192 kHz capability, 120 dB dynamic range, USB-C connection, and Air modes target users who want polished sound in a small setup.
Best For: Solo vocalists, guitarists, and mobile songwriters who prioritize high-resolution recording and included production software.
Pros:
- Provides one XLR mic preamp and one Hi-Z instrument input.
- Supports up to 24-bit/192 kHz recording with a stated 120 dB dynamic range.
- Air modes add presence and harmonic drive to vocals and guitars.
- Includes Pro Tools Intro+, Ableton Live Lite, Cubase LE, and Hitmaker Expansion.
Cons:
- It has only one microphone input and one instrument input.
- The supplied notes do not specify dedicated MIDI I/O ports.
The Scarlett Solo 4th Gen is a strong fit for focused vocal-and-guitar recording rather than larger ensemble sessions. If dedicated MIDI ports are essential, confirm the hardware connections first; otherwise, its high-resolution recording and software bundle are attractive strengths.
How We Picked the Best Audio Interface with Midi Ports
We focused on interfaces that provide genuine MIDI connectivity alongside USB audio recording, rather than treating MIDI as an afterthought. Our evaluation criteria included input and output flexibility, preamp quality, monitoring features, driver and computer compatibility, portability, ease of setup, and overall value.
The list spans beginner-friendly models, compact interfaces for mobile or desktop use, and more capable units for musicians who need multiple analog inputs or real-time effects. Because MIDI requirements vary, check whether a model offers traditional five-pin DIN MIDI, USB MIDI support, or both before buying.
Quick Comparison
| Best For | What to Prioritize | Ideal Interface Type |
|---|---|---|
| Solo vocals and instruments | Simple controls and a quality preamp | One- or two-input interface |
| Keyboard players | MIDI I/O and reliable monitoring | Two-input interface with MIDI |
| Small recording setups | Several analog inputs and outputs | Four-input interface |
| Low-latency production | Direct monitoring and stable drivers | Modern USB interface |
| Mixing with software effects | DSP or bundled processing | Interface with onboard or included FX |
Key Buying Factors for an Audio Interface with Midi Ports
MIDI Connectivity
Traditional five-pin MIDI ports are useful for connecting older keyboards, drum machines, and synthesizers. USB MIDI devices may only require a computer connection, so determine which hardware you plan to use and confirm the exact port type.
Inputs, Outputs, and Expandability
Two inputs are usually enough for one or two microphones, a stereo keyboard, or basic overdubbing. Choose four or more inputs if you record multiple performers, stereo instruments, or several pieces of hardware at once. Line outputs and headphone outputs also matter when connecting monitors, headphones, or external processors.
Audio Quality and Monitoring
Look for clean mic preamps, suitable gain range, and a sample-rate and bit-depth combination that fits your recording needs. Direct monitoring can reduce distracting latency while tracking, while software monitoring may be preferable when you need plug-in effects during performance.
Power, Compatibility, and Workflow
USB bus-powered models are convenient for laptops, but some setups benefit from an external power supply. Confirm operating-system compatibility, USB connector requirements, included software, and whether the interface has the controls you will use most often.
Who Should Buy Which Audio Interface with Midi Ports?
Choose a compact two-input model if you are a singer-songwriter, podcaster, or producer recording one or two sources at a time. A four-input interface is better for keyboardists, small ensembles, and users with several synthesizers or drum machines. Beginners should favor straightforward controls and dependable monitoring over features they may not use. More experienced producers may prefer expanded routing, additional outputs, or integrated effects for a faster hardware-and-software workflow.